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If there is an agreement to disagree sometimes, so be it, but continuing US-Russia dialogue is the only way to figure out which disagreements can ultimately be overcome.
It is concluded that the neo-liberal global economy has facilitated a regulatory 'race to the bottom', a problem that can only ultimately be overcome by international negotiation and agreement.
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These data indicate that senescence may constitute an effective barrier to ALK-induced malignancies that ultimately must be overcome for tumor development.
Deregulation of MYC in BL is undoubtedly a potent promoter of lymphocyte proliferation; however, overexpression of this proto-oncogene also induces powerful antiproliferative, apoptotic stress responses, which ultimately must be overcome for lymphomagenesis.
With modern sequencing technologies, this lack of knowledge can be overcome and ultimately allow the comparison of the genetic networks involved in sex determination and differentiation among closely related species that exhibit different reproductive modes.
The development of metabolic models with advanced tools for examining these limits will enable a better understanding of how metabolic networks are physically constrained and, ultimately, of how these limits can be overcome to expand the possibilities of microbial chemical production.
Finally, we discuss key barriers that must be overcome to fulfill the promise of stem cell biology in preclinical applications and ultimately in clinical practice.
Ultimately, such genetic alterations may allow the proliferation defect of Brca1 deficiency to be overcome, and Brca1-associated tumorigenesis will result.
These problems could be overcome.
This can be overcome.
Things can be overcome.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com