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Reviewer 1: Eugene V. Koonin, National Center for Biotechnology Information, NIH, USA This manuscript addresses what I believe to be the ultimate problem in the study of the origin of cells: the emergence of the translation system.
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In a sense, say some mathematicians and computer scientists, Dr. Rabin may have solved the ultimate problem in cryptography, one that has driven research for centuries: finding a provably unbreakable code that is also practical.
The ultimate problem is to parse the information in the pixel "footprint" images from the drift of the charge cloud produced in the detector layer.
"The ultimate problem is the nonexistence of a political union," said Mr. Krämer, the Commerzbank economist.
Evolution offers much explanatory power and can be helpful when implementing public policy and prevention programs because it allows us as researchers to look deeper at the root cause of these problems, thus aiding us in solving the ultimate problem, rather than simply treating the proximate manifestation of it.
Buddhism is a system of teaching aiming to eradicate the ultimate problem of mental suffering in life.
Such a new awareness would not have represented Kant's first acquaintance with "Hume's problem" (which awoke him from his dogmatic slumber), but it may have been an important step towards Kant's ultimate solution to the problem in the critical period.
But the ultimate problem is that it does not result in money damages for shareholders (and it also means fewer attorneys' fees for the law firms bringing these cases).
That was the ultimate problem with "Controversies".
But the ultimate problem came down to basic economics.
Ah, but then the ultimate problem becomes painfully clear: Where to draw Europe's eastern border?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com