For instance, epigenetic mechanisms have been implicated in the programming of cell fate and differentiation [43] [50], in defining ultimate activity levels of specific functional systems [22], [24], and in mediating environmental modulation of genetically-based developmental programs [22], [24], [42], [51], [52].
It can be concluded that, although the C-terminal 173 amino acids are essential for the ultimate enzymatic activity of TorA, they do not influence the formation or stability of the pre-export complex between TorA and TorD.
Whatever the ultimate identity and biological activity of the cells formerly known as MSCs, the scientific principles that guide their clinical development and use must be the same as those for other new therapies: precision, validation, characterization, objectivity and the abandonment of terms and conceptual models that mislead more than they illuminate.
That distinguishes it from microRNAs, which control many proteins simultaneously.A hypothetical RNAi drug might, for instance, become the ultimate analgesic by affecting the activity of SCN9A, a gene recently pinpointed as the reason why a Pakistani street performer who put knives through his arms and walked on burning coals could not feel pain.
The combined effect of all of these is the ultimate increase of the photocatalytic activity of the ZnO/TiO2 composite.
Adi Da said that what keeps human beings from experiencing this ultimate, enlightened reality is the activity of ego, which he stated is the source of all emotional, psychological, and spiritual dissatisfaction.
There is no doubt that improving the carboxylation activity of Rubisco is the ultimate way to increase the efficiency of CO2 fixation in both autotrophic and heterotrophic microbes.
The ultimate choice of activity rule must depend, in part, on beliefs about the types of bidders likely to participate in an auction event because one cannot have a rule that is simultaneously strong for both budget-constrained bidders and quasi-linear bidders.
With that distinction in mind, we can examine Scotus's argument for the existence of a first efficient cause: Scotus then goes on to argue that there is an ultimate goal of activity (a being that is first in final causality), and a maximally excellent being (a being that is first in what Scotus calls "pre-eminence").
Circulating CD14+ monocytes derive from hematopoietic stem cells in the bone marrow and migrate to their ultimate sites of activity, and form a heterogeneous population in terms of surface markers, phagocytic capacity, and differentiation potential.
