Sentence examples for ubiquitous reduction of from inspiring English sources

We previously identified and cloned the human homologue of TIP60 in Drosophila, referred to as Dmel\TIP60 [26] [26] or dTip60 [5] and demonstrated by GAL4 targeted RNAi knockdown technology [27] that ubiquitous reduction of endogenous Dmel\TIP60/RNAi in the fly results in lethality [6].

Taken together, these data show that ubiquitous reduction of SIN3 levels results in heightened sensitivity to paraquat-induced oxidative stress.

The lethality caused by ubiquitous reduction of methionine metabolic enzymes and histone modifiers led us to further investigate their role in development using a conditional knockdown system.

To examine gene expression changes that result from ubiquitous reduction of SIN3 levels, candidate genes involved in Tor signaling and/or longevity (tor, 4E-BP, S6k, Sod, Cat, Foxo, Sir2) or in the paraquat-induced stress response (Gclc, Gclm, CG32495 and GS) were chosen.

Hence, our study strongly argues against a spatially ubiquitous reduction in cortical metabolic rate from WK to NREMS, but in turn provides support for the view of NREMS as a local phenomenon, emphasizing the predominant role of deep layers.

DHFR is a ubiquitous enzyme that catalyzes the reduction of 7,8-dihydrofolate (DHF) to 5,6,7,8-tetrahydrofolate 5,6,7,8-tetrahydrofolateTHFamide adenine dinusingtide phosphate (NADPH) as a cofactoreduced

TRXs are small, ubiquitous proteins involved in the reduction of disulfide bridges in a variety of target enzymes that are present in all sub-cellular compartments and involved in many biochemical reactions.

(B ) Systemic reduction of growth by ubiquitous expression of Imp-L2 with arm-Gal4 under standard conditions decreases the size of the control eyes but enhances PTEN mutant overgrowth.

Glutaredoxins (GRXs) are ubiquitous oxidoreductase enzymes that mediate reversible reduction of disulphide bonds of their substrate proteins in the presence of glutathione (GSH) via a dithiol or monothiol mechanism.

Cr(V) species are formed during the intracellular reduction of Cr VI), a ubiquitous environmental pollutant.

Consistent with the mouse knockout study, ubiquitous dZnT7 RNAi led to an overall reduction of zinc in the whole body.