Sentence examples for ubiquitous reduction from inspiring English sources

We previously identified and cloned the human homologue of TIP60 in Drosophila, referred to as Dmel\TIP60 [26] [26] or dTip60 [5] and demonstrated by GAL4 targeted RNAi knockdown technology [27] that ubiquitous reduction of endogenous Dmel\TIP60/RNAi in the fly results in lethality [6].

Taken together, these data show that ubiquitous reduction of SIN3 levels results in heightened sensitivity to paraquat-induced oxidative stress.

The lethality caused by ubiquitous reduction of methionine metabolic enzymes and histone modifiers led us to further investigate their role in development using a conditional knockdown system.

Hence, our study strongly argues against a spatially ubiquitous reduction in cortical metabolic rate from WK to NREMS, but in turn provides support for the view of NREMS as a local phenomenon, emphasizing the predominant role of deep layers.

To examine gene expression changes that result from ubiquitous reduction of SIN3 levels, candidate genes involved in Tor signaling and/or longevity (tor, 4E-BP, S6k, Sod, Cat, Foxo, Sir2) or in the paraquat-induced stress response (Gclc, Gclm, CG32495 and GS) were chosen.

Reduced adiposity is a phenotype that, although also consistent with one of the classic symptoms of type I diabetes in humans, had not previously been observed in flies with a ubiquitous reduction in insulin signaling or lacking the systemic Ilp peptides (puzzlingly, these flies were actually found to accumulate triglyceride; Böhni et al., 1999; Grönke et al., 2010).

Compared with controls, in patients with myotonic dystrophy type 1 we detected ubiquitous fractional anisotropy reduction in association fibres: bilateral superior and inferior longitudinal fascicles, inferior fronto-occipital fascicles and uncinate fascicles, both fornices, cingulum bundles and hippocampal parts of the posterior cingulum bundle.

Tetrazolium reduction is a ubiquitous property of cells, enabling a simple colorimetric cellular assay technology to be multiplexed into thousands of different assays and facilitating detailed cellular analyses in what we term Phenotype MicroArrays [3] [6].

DHFR is a ubiquitous enzyme that catalyzes the reduction of 7,8-dihydrofolate (DHF) to 5,6,7,8-tetrahydrofolate 5,6,7,8-tetrahydrofolateTHFamide adenine dinusingtide phosphate (NADPH) as a cofactoreduced

TRXs are small, ubiquitous proteins involved in the reduction of disulfide bridges in a variety of target enzymes that are present in all sub-cellular compartments and involved in many biochemical reactions.

Cr(V) species are formed during the intracellular reduction of Cr VI), a ubiquitous environmental pollutant.