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In metazoans, the SH2-kinase core is typically flanked by additional regulatory domains, such as SH3.
For example, Alu insertions are typically flanked on both sides by target sites for LINE-1 endonuclease.
The genomic breakpoints are typically flanked by IS-elements and associated with a large number of pseudogenes [ 8- 10].
This interpretation is consistent with the finding that eukaryotic transcriptional start sites are typically flanked by well-positioned nucleosomes.
These rearrangements are believed to be created by IS-elements and the elements are typically flanked by pseudogenes [ 8- 10].
This observation together with the fact that SLG clusters are typically flanked by several transposases or remnants thereof indicate that the entire SLG region may be a subject of HGT in bacteria.
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In the case of X. tropicalis, we find that the genes typically flanking SCD5 in other tetrapod species are present but in different scaffolds).
While each prohormone precursor possesses a distinct primary sequence, proteolytic processing occurs at dibasic residue sites that typically flank the NH2 and COOH termini of neuropeptides within their precursors (Fig. 2) (9– 11).
The decision of editing was based upon the identification of manifest errors in the automated predictions, such as the prediction of a four base pair intron 5'-CCCT-3', missing the consensus GT-AG sequences typically flanking introns for the Ag-3 predicted transcript (XM_309157).
10 The Lynx medical record used by emergency clinicians during the study period is a templated, handwritten chart that specifically prompts clinicians for the presence or absence of factors related to the chief complaint selected (typically flank or back pain), and was well suited to determining the presence or absence of factors.
According to Jun et al. [ 43] orthologous genes typically share homologous neighbouring genes, while non-orthologous genes are typically not flanked by homologous neighbours.
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