In summary, the literature illustrates that ERs exist in skeletal muscle, but whether or not they display typical steroid receptor responsiveness to their ligand, i.e., estradiol, has not been studied in intact skeletal muscle.
A typical PBMC response in patients during the chronic intestinal stage is characterized by lower anti-SEA (soluble egg antigen) responsiveness in contrast to higher anti-SWAP (soluble worm antigen preparation) responsiveness [ 2, 3].
There were only 3 patients developing typical asthma whose bronchial responsiveness was more increased among the patients not taking ICS and was not obviously increased after the asthma onset as shown in Fig. 1.
Moreover, body positioning is a typical manoeuvre for assessing fluid responsiveness [ 1, 6].
Active NOTCH signaling is required for normal mammary stem cell function [ 92], implying that the development of endocrine therapy resistance in breast cancer cells may rely on the reversion or reactivation of stemness pathways and a loss of estrogen responsiveness that is typical of luminal breast cancer cell identity.
"I might suspect, on the basis of typical male signals (aggressiveness, big moves, responsiveness to percussive rhythms) but I could easily be fooled.
Pathophysiological features of cough variant asthma [ 2] appear to be similar to typical asthma, with mildly increased bronchial responsiveness and eosinophilic inflammation of central and peripheral airways, and a cough responsive to bronchodilator therapy [ 3].
In interviews, parents, who requested anonymity because they have children at the school, called the incident typical of the lack of transparency and responsiveness at many state-run institutions in China, which are unaccustomed to any form of public scrutiny.
Bronchial responsiveness did not further increase after onset of typical asthma in 3 patients not taking ICS.
To assess whether these changes may distinguish AtCRT3 functions from that of typical CRTs, we measured the ER Ca2+-holding potential and the responsiveness to BK of the AtCRT3 complemented crt−/− mouse fibroblasts.
