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HIBM muscle fibres present typical pathology, with rimmed vacuoles and cytoplasmic and/or nuclear filamentous inclusions.
Our search for an experimental model that recapitulates typical pathology features of severe malaria in pregnancy revealed that time of infection during pregnancy is critical to evidence poor pregnancy outcome and fetal growth impairments.
b"Involved" refers to the presence of typical pathology.
A typical pathology for TP on pleura biopsy was associated with a better outcome.
The typical pathology of MFM is best visualized in H&E and modified Gomori trichrome (GT) stains (Fig. 1a, b).
As in skeletal muscle biopsy, the extent of typical pathology is highly variable in cardiac specimens from desminopathies.
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Typical pathologies in these newborns include perinatal brain injury and bronchopulmonary dysplasia (BPD), among others.
Multi-dimensional machine learning methodology was used to identify associations between ten typical pathologies in 6485 batches of slaughtered finishing pigs, assisting the comprehension of their biological association.
Applying this methodology to the data comprising of the typical pathologies present in slaughtered finishing pigs has led to an easy to interpret, highly visual, and statistically robust output: a network in which the main associations between the pathologies are easily identifiable.
Mouse models mimicking AD-typical pathology, such as deficits in synaptic transmission [ 24], changes in behavior, differential glutamate responses, and deficits in long-term potentiation are typically based on the overexpression of full-length amyloid precursor protein (APP) [ 39].
Although many of the risk factors are likely to affect cognition through an influence on cerebrovascular disease, on AD-typical pathology or on both, underlying pathophysiological mechanisms are not the main focus of this article, and these have been reviewed extensively elsewhere [ 6– 8].
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