These include a typical molecular mass being in excess of 10 kD, relative unstability of unmodified RNA aptamers, and possible off-target effects.
Cytolytic RTX leukotoxins (Table 1) are proteins of a typical molecular mass of 100 120 kDa that possess similar structural and functional domains and are encoded within similar rtx operons as the RTX 'hemolysins' (Fig. 3) (Chang et al., 1987; Lo et al., 1987; Lally et al., 1989;).
Typical molecular masses of isolated lignin are in the range 1,000 to 20,000 g/mol, but the degree of polymerization in nature is difficult to measure, since lignin is invariably fragmented during extraction from living matter.
GSTs are soluble proteins with typical molecular masses of around 50 kDa, each composed of two polypeptide subunits.
The perturbation of a flat, premixed, fuel-rich propene/oxygen/argon flame at 50 mbar by a sampling nozzle used in typical molecular beam mass spectrometry (MBMS) experiments was analyzed.
Non-denaturing PAGE and western-blot analysis of cell lysate from PC12-Wt cells showed a single band characteristic of monomeric wild-type neuroserpin (Fig. 4A, bottom panel, lane On/Wt, arrow), while PC12-S52R and PC12-G392E celysatesteshoweded high molecular mass ladders typical of polymers (Fig. 4A, bottom panel, lanes On/S52R and On/G392E, curly bracket).
Fungal enzyme XynA is thermostable with a relatively small molecular mass; it forms typical inclusion bodies in both the cytoplasmic and periplasmic spaces of E. coli during high-level expression under normal conditions (Fig. 1A, B).
For the objects with exospheres (Mercury, the Moon, Ganymede, and Callisto) we estimate the total neutral gas mass as where H is the typical scale height of the exosphere, N is the typical surface density, and m is the molecular mass of the main constituent.
One drawback of fluorescent proteins based on GFP is their relatively high molecular mass (26.9 kDa) compared to typical target proteins.
The classical strains, Dawson, SSBP1 and MRI Suffolk scrapie display the typical classical scrapie molecular phenotype; a high relative molecular mass un-glycoslyated band, which is reactive to the N- terminal antibody P4.
Similar mass spectra were detected in which typical molecular ion [M]+ at m/ z 370 and fragmentation clusters surrounding at m/ z 307 [M-CH3-CCl]+, 279 [M-CSO2CH3]+, and 184 [M-SO2CH3-3Cl]+ were displayed.
