Sentence examples for typical linkage from inspiring English sources

Another group of fragments is directly related to these typical linkage reactions.

Because approximately 2.8 Mb separates these markers, a distance far in excess of typical linkage disequilibrium values in the Indian population [23], we conclude that these two SNPs are not independently linked to a separate single causative mutation.

Since any errors that occur in the analysis of one pedigree will be multiplied when multiple pedigrees are aggregated in a typical linkage analysis study, it is important that our method perform accurately when only a small amount of data is available.

On average, a typical linkage group comprised 30 markers (Table S4).

A typical linkage study will report all loci with LOD scores greater than three, which corresponds to the data being 1000 times more likely to arise due to cosegregation with disease than by chance [9].

For a typical linkage analysis, the raw data consist of genotypes at many genetic markers for a collection of individuals from one or more families and a measured phenotype that is either discrete or continuous.

Note that the effect of locus frequencies in association mapping studies differs from typical QTL linkage mapping in experimental populations, where marker frequencies are under experimental control due to breeding designs and are often equal among alleles.

The overall distribution of the markers was typical for linkage groups constructed for plant species with moderate to large sized genomes, with marked clustering (reduced recombination) around the putative centromeric regions and higher levels of recombination towards the ends of the linkage groups.

The defect clustering of Ti2+, Ti4+, and H+ co-doped Ti2O3 through Eqs. 1 and 2 may be effective as soon as the oxolation by forming Ti O H linkage, typical in a hydrothermal process [51], caused considerable polymerization and various defect clusters in the crystals as observed by TEM.

In typical GWAS studies, linkage analyses are performed, where each SNP is tested for association with a specific phenotype of a disease.

Typical measures of linkage quality have used samples of links to gain an estimate of quality, often able only to estimate the number of incorrect links created, with the number of links missed essentially unknown [ 25], or have used relative measures to estimate missed links [ 26] which allows relative comparison, but not absolute quality measures.