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The second unit, "The Disease," explored the differences between typical ageing and dementia, risk factors for dementia, symptoms, diagnosis, and medical management.
In particular, the strongest associations with our measure of brain ageing were found with information processing speed measures, and impairments in this domain have been posited as central to the cognitive decline associated with typical ageing.
In the context of the world-wide increase in the number of adults over the age of 65 years, there is a need for all members of society to understand issues in ageing, and how dementia is not part of typical ageing but rather involves progressive and degenerative pathology in the brain.
Conversely, the reduction in the frequency of the common deletion in liver tumours indicates that there is an active selection pressure against the presence of mtDNA with large deletions, or more controversially that a population of liver cells do not undergo the typical ageing response and subsequently form the liver tumour.
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Defects in genome maintenance in the Ercc1 -/Δ progeroid mouse model result in premature aging and typical age-related pathologies.
Recognition and high-profile commissions, if they materialize at all, typically arrive in an architect's 50s — well past the typical age for starting a family.
Heart failure (HF) is a typical age-associated disease and is characterized by unique physiological and morphological changes in aged myocardium [reviewed in (Lakatta & Sollott, 2002)].
"There's no typical age group, or sex, just, well, regular folk," he said.
I was 26 – a fairly typical age to receive the fateful news.
The typical age of onset for anorexia is between the ages of 12 and 25.
The typical age of onset is in the 20s, but it may occur at any age.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com