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These types of deletions may occur via homologous recombination.
Here, we extend the duplication distance measure to include certain types of deletions and inversions.
Both types of deletions, however, result in the loss of a locus that often contains multiple genes.
We have shown how to generalize duplication distance to include certain types of deletions and inversions and how to compute these new distances efficiently via dynamic programming.
A striking feature of the data (Taylor et al., 2014) is that the types of deletions found in any two samples are almost completely different (Supplemental Note 1).
Understanding evolutionary processes that drive genome reduction requires determining the tempo (rate) and the mode (size and types of deletions) of gene losses.
Similar(42)
We assume that both types of deletion data, as well as perturbation data, are available, although it is trivial to modify our algorithm by simply removing the corresponding subroutines if any type of data is missing.
Lifespan is normal for all three types of deletion mice.
And in the current study we show further phenotypic differences between the two types of deletion mutants.
Similarly, any two cells with clonal expansions from the same sample usually carry different types of deletion.
The types of deletion mutants can be divided into single exon deletions, multiple exon deletions (2 8 exon deletions), and mutants in which all nine exons had deletions.
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