An association with age at menopause was seen for squamous cell carcinoma (RR per 5 years younger at menopause, 1.32, 1.11 1.56) but not for adenocarcinoma (0.98, 0.78 1.23); the difference between the 2 types was of borderline statistical significance (P heterogeneity, 0.04).
BMI, height and number of pregnancies were insignificant effects, and mean breast volume and parenchyma type were of borderline significance (results not shown).
In addition, mesothelioma type became of borderline statistical significance (P=0.076) due to a statistically significant shorter latency for those with pleural and peritoneal mesothelioma compared with those with just pleural mesothelioma (TR=0.83, 95% CI=0.74 0.92).
Although the statistical significance of the difference observed between the two types of regimen is borderline (p = 0.06 Mann-Whitney U test), this result suggests that a more frequent treatment even with a lower dose could be at minima as efficient, in good agreement with the short half-life of GA in vivo, i.e. a couple of hours in the human body [23].
The 6 cases of benign tumours with SLP-2 overexpression included 5 serous and 1 mucinous type; The 9 cases of borderline ovarian tumour with SLP-2 overexpression included 6 serous tumour, 2 mucinous tumour, and 1 mixed tumour.
We developed and temporally validated a prediction model that is able to discriminate between five types of adnexal tumour (benign, borderline, stage I cancer, stage II-IV cancer, and secondary metastatic cancer), while still showing excellent overall discriminative capacity between benign and all malignant tumours.
Whole-body vibration was associated with severe disc degeneration at L5-S1, whereas it was of borderline significance in case of type II Modic changes at L5-S1.
Once the age of the child is controlled for, then the relationship between HPV type and clinical course becomes one of borderline significance.
MicroRNA expression was further analysed according to lesion type in the two largest groups of borderline lesions as compared with benign naevi (ratio of fold change).
Occupation (train engineers vs. sedentary factory work) or the duration of exposure to whole-body vibration was of borderline significance for type II Modic changes located at L5-S1.
