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Multiple types of adherence measures meant that agreement between measures could be assessed.
The purpose of the ADQ was to measure a unitary concept of adherence across different types of adherence behavior.
The first two types of adherence measure predicted gains in weight and CD4 count; consistent visit attendance was associated only with weight gain.
On the other hand, it was demonstrated that the availability of various types of adherence support may avoid attrition to antiretroviral therapy [ 15].
The aim of this study was to explore which types of adherence interventions, and their underlying theoretical perspectives, are promising for future research and development.
The limited sample size did not allow us to separately evaluate the effect of the intervention on the two types of adherence error (i.e. unintentional or intentional).
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The fact that the proportion of patients classified as non-adherent increased from 11% to 38% depending on the type of adherence measure used (i.e. dose adherence versus adherence index) indicates that patients often are classified as being adherent when only the number of missed pills during the last few days are assessed.
However, reviews may focus distinctly on one aspect of adherence behaviour, for example, appointment keeping, drop-out, or medication taking, or on one type of adherence intervention, for example medication packaging, financial incentives, or patient education.
aEPEC strains representing each HEp-2 cell type of adherence were analyzed after 24 h and 6, 12, and 18 days of incubation at 37°C on abiotic and cell surfaces by CFU/cm counting and confocal laser scanning microscopy (CLSM).
The first 12 are single-focus reviews that include one type of adherence interventions, for example technical solutions such as, simplifying dosage or packaging, behavioural interventions, educational interventions, or social support.
* Derived from Vervoort review [ 20] and grouped by WHO [ 21] type of adherence risk factor The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-2288/11/124/prepub Marie Curie Cancer Care funded this project.
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