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The modifications were applied to wild type sequence in order to mitigate its immune-reactiveness.
These input areas are partially responsible for changes in the type sequence.
The first column denotes the wild type sequence, second column the average unfolding propensity at the location, third the foldability, fourth the information entropy, fifth the residue depth.
Most of the formations representing the type sequence are found in Missouri, Iowa, and Illinois.
A new site adds a whimsical element: the Most E-Mailed Photos site (www.mostemailed.com) strings together the three most forwarded photos from Yahoo each day and invents captions for them to create a comic-book type sequence or story.
In addition, Vela has the wild type sequence with an arginine at position 495.
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Inset, ribbon model with wild-type sequence.
Black boxes, wild-type sequence; White boxes, mutated NF-κB-binding sites.
The latter is a saturation recovery-type sequence that involves cross-polarization.
Notably, 93% of the HMA-negative samples that we sequenced contained a small indel compared with the wild-type sequence (Supplementary Information tab 3).
(b) Typical sequencing traces are shown for exons 9 (right) and 20 (left) with cancer mutant sequence (bottom) and normal wild-type sequence (top).
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