Suggestions(1)
Exact(3)
Similarly to the cervix, most of the vulvar (pre)neoplastic lesions are induced by HPV infection (most commonly HPV 16), except for the "differentiated" (simplex) type of VIN.
The pathogenesis of HPV-negative cancers is less well understood, but these cancers frequently arise on a background of lichen sclerosus, squamous cell hyperplasia and simplex (differentiated) type of VIN.
In eight cases, the subdivision was impossible because the diagnosis of the type of VIN lesion was uncertain because of massive intraepithelial inflammation, epithelial destruction due to massive ulceration or because the required tissue was not available.
Similar(56)
In conclusion, we found that p53 immunoreactivity in VIN is associated with the presence of invasive disease, implying that any case of VIN staining positive for p53 should be checked carefully for the presence of occult invasion.
Samples obtained were as follows: 43 cases of lone VIN III, four cases of lone VIN II, five cases of lone VIN I, 49 cases of VSCC and 21 cases of VIN associated with concurrent VSCC.
Histological grading of VIN based on H/E sections does not always accurately distinguish between VIN 2 and VIN 3 (van Beurden et al, 1999).
In summary, HDACs, the targets of HDACi, are highly expressed in the majority of VIN and VSCC and show a different expression pattern among these two tissue types irrespective of the HPV-related etiology.
Think of Vin Scully and the Dodgers.
There was the brief and erroneous coronation of Vin Diesel.
The distinctiveness of Vin Jaune extends to its appearance.
Or dip firm biscotti into a glass of vin santo.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com