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But when Nowell was examining the Azraq artifacts in her lab a few years ago, a colleague suggested she send some of them out for a type of residue analysis called "immunoelectrophoresis". If any bits of blood or tissue were left on the tools, this test could tell her what animals the ancient humans were hunting.
The pairwise statistical potential EPAIR requires five distinct symmetric matrices, where a and b vary among the 20 aminoacid types, for overall 1050 parameters: ai is the aminoacid type of residue at position i, and xij is the structural class to which residue pair i - j is assigned.
Compilation of a database of 94 epitope/flanking region combinations, for which immunogenicity was measured experimentally, revealed that the type of residue immediately following the carboxyl-terminus of the epitope exerted a prominent effect on immunogenicity.
The network is formulated as a mixed integer linear programming problem selecting the type of residue, the number and size of the digesters and the location of the plants across 59 shires of a particular region in Spain for the available budget.
The statistics are available for both atomic and residue charges, and are computed for relevant properties such as chemical element, type of residue, etc.
The 'residue1' or 'residue3' tag specifies what type of residue is constrained.
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A limitation of current 3C methods is that they depend on a single crosslinker, formaldehyde, which has known biases in the type of residues it can crosslink.
Additional refinements of the M antigen model were performed using a similar minimization protocol in which the type of residues constrained during the minimization were varied: initially, only residues out of the most favored regions of the Ramachandran plot were allowed to move, then residues with a high model B-factor and/or force field energy were included.
In this method, each type of residues was coded with 21 binary values, for example, 100⋯0 (one followed by 20 zeros) for Cys and 010⋯0 for Ser.
The possible number and diversity of nontemplated junctional nucleotides is theoretically nearly infinite and position independent, but structural constraints limit the length and type of residues encoded in junctions.
Conservation between the human and Dicyema sequences was more strongly observed in the DNA-contacting aa residues (36/37) than in non-contacting residues (64/92) (P < 0.001 by Fisher's exact test), suggesting the functional importance of the former type of residues.
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