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Finally, although we hypothesize that the discrepancy between the present study and previous publications was related to the type of included patients, we did not directly compare the device in similar conditions between critically ill and perioperative patients.
This appears to distinguish them from the immunity proteins located within a regular polymorphic toxin locus in which only the complete toxin gene and its adjacent immunity protein are expressed [ 181]. 3) The polyimmunity loci show considerable differences in terms of the number and type of included immunity genes, even between strains of the same species.
The subgroup analysis stratified on the type of included patients in primary studies, however, disclosed a statistically significant reduction in mortality in the studies that restricted inclusion to only patients with ARDS, and not in those also enrolling patients with less disease severity.
We extracted data from included studies, using a piloted data extraction form, on the following: number and type of included studies, number of participants, target population, location of the studies, key conclusions, knowledge gaps and reporting quality.
They might be explained by differences in the type of included defects, surgical flap design, surgical skills, or case selection [ 38].
Information such as the number or type of included studies and whether quality appraisal of studies was performed, were extracted to help explain potential differences (if applicable) in results between the benchmark and non-benchmark paper.
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First, the major difference is the type of population included.
Type of treatment included 'medical'surgeryery' or 'other'other
We included all types of RCTs, including cluster RCTs, and nested designs.
(Examples of this type of disease include hemophilia and a form of red-green color blindness).
Other institutions offering variations on this type of programme include the universities of Bath and Glamorgan.
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