Exact(6)
A new type of gating has been realized which allows a flexible control of transmission or reflection by the crystal plates.
This type of gating is widespread among K+ channels, where the glycine hinge is highly conserved [31], in particular in K2P channels, which have hinge glycine residues in their TM2 and TM4 helices [22].
A second type of gating is thought to occur by a sort of constriction of the selectivity filter, first recognized in the form of C-type inactivation [33], and is sensitive to mutations at residues neighboring the external entrance of the pore.
This type of gating is analogous to phenomena often observed with peptide loops in enzymes.
This type of gating may enable oscillatory network activity between different brain areas involved in learning (Buzsaki and Draguhn 2004).
However, the precise nature of this and other proposed gating functions remains under debate (Shastry and Hancock, 2010) and, similar to the monomer mechanism itself, there is little consensus on the structural basis of any type of gating mechanism in dimeric kinesin (Sindelar, 2011).
Similar(54)
We propose to use different types of gating network functions to handle both categorical and continuous variables in the integrative ME approach.
(In a logic gate, the two inputs produce one output of a certain value, depending upon the type of gate and the value of the inputs).
Cooperative quadratic Boolean input-output systems can use only binary AND, binary OR, and unary COPY gates; the latter type of gates is not allowed in strictly quadratic input-output systems.
Three-quarters of the sculpture's external surface reflects the sky and the name refers to it acting as a type of gate that helps bridge the space between the sky and the viewer.
A further type of gate mechanism, the ball-and-chain inactivation, has not been reported for K2P channels.
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