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The standard safety test design for this type of endpoint was developed in the mid-1960's and has changed little in the ensuing half-century.
This type of endpoint has been used previously in clinical trials in which survival outcomes have been shown to be similar between treatment regimens; thus, a regimen that reduces the risk of toxicity is clinically relevant, particularly in the palliative setting.
This interpretation algorithm has knowledge of the type of endpoint injected into the assessment algorithm.
The major disadvantage of standard test methods is that it does not always represent the most biologically relevant testing approach depending on the type of endpoint under investigation.
We designed Google Voice to be endpoint-agnostic and we certainly want it to be accessible from any type of endpoint, not just phones," Paquet told eWEEK June 21.
Analyses were made to examine whether the percentage of positive studies was dependent on the following: biological agent used, type of endpoint measured, dose and time of exposing nano-TiO2, exposed route, and nano-TiO2 diameter.
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The literature provides little evidence on what type of endpoints should be used to assess treatment‐induced improvement in female sexual function.
No indication is provided on the type of endpoints to be assessed, of the methods to be used, or of the approach (laboratory or field) to be applied.
They need to consider the type of endpoints; the number of patients in the final analysis; reasons of patient's dropouts; the similarity of the trial with the previous trial(s) that established the efficacy profile of the comparator; and the constancy assumption of the data used as reference for the NI margin.
Talk to a typical CFO about the types of endpoint and datacenter protections you've implemented, and before long you're likely to see her eyes glaze over.
Where more thought and research is required is how to combine results from different types of endpoint.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com