Under electrical stimulation (6 Hz, 37 °C) KI EHTs exhibited shorter contraction and relaxation times and a twofold higher sensitivity to external [Ca2 +].
As a consequence, a twofold increase in sensitivity was gained without sacrificing specificity.
For instance, patients with G6PD-deficient erythrocytes reveal about a twofold increase in sensitivity towards sulfone-induced anaemia.
Results showed a roughly twofold increase in sensitivity to IR and cisplatin after expression of SYCP3 (Fig 1E,F).
Thus, decreased PKR expression in engrafted leukemic cells results in an almost twofold reduction in sensitivity to a single treatment with DOX in vivo.
Relative to N2, all dat-1 mutants, as well as vt29, exhibited a statistically significant, twofold increase in sensitivity to exogenous DA on solid substrate.
We demonstrated that spatial unwrapping led to a twofold improvement in sensitivity, averaged over cones, and that in single cones failure to unwrap could generate the worst possible phase errors.
For the leukaemic cell lines, only a twofold range in sensitivity to THYMITAQ was observed (IC50 0.87-2.3 microM), and this did not correlate with TS activity, TS protein or TS mRNA levels.
Combined with the higher affinities for glucose, the result indicates an approximately twofold increase in sensitivity to changes in the glucose concentration in the range 0 10 m m (see Figure S182).
Furthermore, Ko143 rendered Caco-2 LF/FA cells about twofold more sensitive to gefitinib, suggesting that BCRP does have a function in gefitinib sensitivity in these cells.
The study proved interesting for the benefits of food sensitivity testing twofold: Not only did research show that those in the migraine group tested significantly higher for food allergens than the control group, but that elimination diets also reduced migraine frequency and strength without the aid of pharmaceuticals or other forms of therapy (6).
