A further twofold reduction in transforming activity was observed with insulated LCR-containing LV.
A twofold reduction in risk, with a p value trending toward significance, may be statistically insignificant, but still clinically relevant.
Low doses led to a 2.6-fold increase in mercapturic acid, while higher doses resulted in a twofold reduction of a byproduct of the carcinogenic metabolite.
We note, also, that the point mutations produced only a twofold reduction in the potency of our control compound NITD609, a low-nanomolar spiroindolone-pocket-binding ScPma1p inhibitor [17] (Additional file 1: Figures S1B and S3C).
The effect of tariquidar on Q out in humans was apparent during and immediately after tariquidar administration (twofold reduction in Q out) but was negligible in the second PET scan.
We identified seventeen phages with a greater than twofold reduction in ELISA signal from the DNase I plate relative to the actin-only plate, and sequenced each of these.
Dazl and Magoh2 showed a twofold reduction in expression.
These effects were associated with a more than twofold reduction in embryonic expression of Pitx2c.
Activity varied strongly among tumors; nevertheless, we observed a twofold reduction in activity.
We suggest that the mechanism is twofold: reduction of bird abundance and shift of foraging behaviour.
Indeed, an approximately twofold reduction in the steady-state level of IRF1 mRNA was observed.
