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The phrase "twofold limitations" is correct and usable in written English
You can use it to refer to something that has two distinct limitations or constraints. For example, "The twofold limitations of the project made it difficult to complete on time."
Similar(60)
Non-polymerisation of the targeted molecule region contributes to a twofold electrophoresis limitation, another being the destructed molecular structure acted by SMFP.
Nicholas terms this a twofold "otherness" that conditions and limits all sensory perception, limitations that we are implicitly aware of in making perceptual judgments.
The limitations for this are twofold: technical and theoretical.
The limitations of our study are twofold.
Limitations to our study design are twofold.
This limitation can be addressed by a twofold model, optimizing for ambulance and private vehicle travel.
The limitations from the retrospective nature of the study are twofold.
These limitations in the design of the observation model are addressed twofold.
Limitations to the findings of our study are at least twofold.
The task is twofold.
His strategy was twofold.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com