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For females, 32 miRNAs are consistently female biased in the soma (more than twofold; Figure S2B).
Pretreatment with LGG increased the number of surviving crypts approximately twofold (figure 2A).
ATF4 mRNA levels were also induced with the peak at 4 h of hypoxia exposure (twofold; Figure 4f).
Volcano plot analysis shows significant differential expression of ion channels between these two subsets (IB4−SNS-Cre/TdT+: 29 genes, IB4+SNS-Cre/TdT+: 16 genes, p < 0.05; twofold, Figure 9C-i).
We first compared SNS-Cre/TdTomato and Parv-Cre/TdTomato neurons, yielding many differentially expressed (DE) genes in each neuron subset (SNS-Cre/TdT+: 907 genes, Parv-Cre/TdT+: 774 genes, p < 0.05, twofold; Figure 8A, Supplementary file 1).
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Simultaneously, the air electroconductivity experienced a twofold decrease (Figure 1c).
In these cells, hyperacetylation of histones at the human MYC promoter is similar to that of the mouse MYC promoter, within a twofold range (Figure 2, lower graph).
In addition, miR-34a overexpression decreased SIRT1 expression by approximately twofold (P<0.01; Figure 3c) with a concomitant increase in p66shc expression.
Numerical values for specific binding (BP ND = k 3/k 4) throughout the brain regions varied twofold (Table 4, Figure 4).
The beam path is represented by the weighting values w n as shown for the twofold DM in Figure 5b.
Motifs including ZDRE, ABRE, and DRE consensus sequences were found at particularly high frequencies within 500 bp upstream of the TSSs of over twofold upregulated genes (Figure 4E, F, H, I).
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