Particularly, the maximum at 450 nm in spectrum 2 can be associated with twofold Si-oxygen deficiency center O2 = Si: [22,23].
The TATA-box motif existed most frequently within 50 bp upstream of TSSs of genes that were induced more than twofold by Fe deficiency (Figure 2E, F).
Furthermore, IDEF1BS was found most frequently 500 bp upstream from the TSSs of genes that were induced more than twofold by Fe deficiency, whereas IDEF1BS was not common within 500 bp upstream of the TSSs of all genes (Figure 2C).
107– 109 The main reasons for vitamin D deficiency are twofold: a lack of adequate exposure to sunlight; and shortage of a dietary vitamin D source.
The drain of choline caused by folate deficiency is twofold: decreased synthesis of choline through the PEMT pathway, and increased use of choline (via BHMT) as a source of methyl groups.
Black lines, frequency of motifs in random and 650-bp sequences; blue lines, number of motifs in all genes; red lines, number of motifs in genes upregulated over twofold in response to iron deficiency.
In our current meta-analyses, frequency of ferritin deficiency increased by twofold in patients at 6 months after surgery, and this trend became substantially aggravated at 24 and 36 months.
In total, 2220 genes changed expression more than twofold (up or down) as a result of Sp1 deficiency, with 564 deregulated genes in Flk1+ cells and 1374 deregulated genes in progenitors (Fig. 3D).
Indeed, Chop deficiency attenuated UUO-induced caspase 3 expression by onefold and Bax expression by twofold.
Interestingly, it seems that TLR4 was probably the primary receptor for Hmgb1 in our model of UUO-induced renal fibrosis as Chop deficiency did not affect UUO-induced expression of TLR2 and RAGE but attenuated TLR4 by twofold.
This putative tartrate-resistant acid phosphatase (Os10g02750) was the most P-deficiency-inducible phosphatase in roots with a sevenfold upregulation in both genotypes, albeit at a twofold higher overall level in Nipponbare.
