However, one still has to account for the twofold higher association constant of Reaction 13 and the twofold higher dissociation constant of Reaction 14.
Indeed, earlier studies show a twofold weaker association of FAPP1-PH with PtdIns(4,5 P2 over PtdIns(4 P-containing vesicles, the latter of which are bound with a KD of 230 nM (Stahelin et al, 2007).
Five IL-4R single nucleotide polymorphisms showed evidence of association (twofold increased risk).
For mothers with both GDM and obesity, the association was twofold for having a child with ASD compared with controls.
Table 2 shows that uncontrolled blood pressure retained a nearly twofold higher probability of association with incident diabetes, independently of all covariates, including treatment.
Significantly, we found that loss of Jhd2 caused an approximately twofold increase in the association of Tof2/Csm1/Lrs4, but not Fob1, with the NTS regions, with greater concentrations of these proteins at NTS1 than at NTS2.
The purpose of our systematic review of case control studies is twofold: (1) to estimate the association between influenza infection and AMI and (2) to estimate the association between influenza vaccination and AMI.
The objectives of this study are twofold: 1) to analyze the association between the availability of municipal emergency care centers and utilization of primary care emergency centers (PCEC), in a Spanish region with high population dispersion; and 2) to determine healthcare providers' perceptions regarding PCEC utilization.
The purpose of this study was twofold; first to examine the association of kidney function with self-reported frailty, using a direct measure of kidney function and estimated GFR as a comparison, and second, to determine whether self-reported frailty was associated with death in this cohort with few comorbidities.
First, the small number of esophageal cancer patients was underpowered to detect a smaller association of less than twofold with the double homozygous BRM variants.
Our calculations show that the association rate constant, k1, suffers a modest twofold penalty in vivo (Table 3).
