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A phase 2 study (Calabrese et al., 2010) and two subsequent phase 3 studies (Calabrese et al., 2014; Ketter et al., 2015) previously evaluated the efficacy and safety of adjunctive armodafinil treatment for depressive symptoms in bipolar I disorder, both using the same primary efficacy measure (IDS-C30).
These remarkable findings of crizotinib activity led to two subsequent phase III clinical trials of this drug.
Two subsequent phase III immunotherapy trials with humanized Aβ-specific antibodies both failed to achieve their primary endpoints – a change in cognitive and functional performance compared to a placebo [ 39, 40].
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The fatigue short crack life can be schematically divided into two subsequent phases: microstructurally short crack and physically short crack.
The oxidation had two subsequent phases: (1) the oxidation of the neutral aniline molecules and the initially produced low-molecular weight aniline oligomers at low acidity, followed by (2) the oxidation of the anilinium cation after the acidity became higher.
The technique is based on two subsequent phases.
The overall process of classifying unknown files as either benign or malicious using ML methods is divided into two subsequent phases: training and testing.
Most tag identification protocols can be separated into two subsequent phases: Tag acquisition refers to the process of obtaining information about the activated tags in order to communicate with them.
The technique makes use of images from two subsequent phases to predict the flow field.
The long-term treatment phase will be followed by two subsequent phases: a discontinuation phase and a restabilization phase, identical to those described in Study 1.
Heart rate initially decreased in phase T2, but was increased in the two subsequent phases, with a parallel increase in MAP and a decrease of APP.
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