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Amidation is catalysed starting from a glycine-extended prohormone, by two sequential actions of two enzymes, peptidylglycine α-hydroxylating monooxygenase and peptydilamido-glycolat lyase.
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Four sequential action research cycles built upon baseline data including 614 acute hip-fracture inpatients and 30 purposefully sampled clinicians.
4 Amyloid peptides are generated by the sequential actions of two enzymes, ie, β-secretase (BACE1) and γ-secretase.
This polyubiquitylation is achieved by the sequential actions of three enzymes: an E1 ubiquitin-activating enzyme, an E2 ubiquitin-conjugating enzyme and an E3 ubiquitin ligase.
This polyubiquitylation is achieved by the sequential actions of three enzymes: an E1 ubiquitinactivating enzyme, an E2 ubiquitin-conjugating enzyme, and an E3 ubiquitin ligase.
In particular, when sequential actions of the two drugs are essential to cause a synergistic effect of the drugs, the time-differential release of each drug from the dual drug-encapsulated carrier is highly important.
Sequential actions of these two RNA polymerases are thought to be essential for chloroplast differentiation.
This may take different forms but one possibility is that binding of one head promotes binding of the other in a way that sequential actions of the two heads are promoted [ 110, 160].
Modeling based on data showing two-headed attachment of fast myosin II [ 100] hinted [ 110] that sequential actions of the two heads of myosin II may become important in shortening against intermediate loads [ 60, 110] (intermediate velocities) when power-output is maximal.
For instance, if the myosin heads are assumed to act independently, it means that neither propagating structural changes in the thin filaments nor sequential actions of the two partner head are assumed to alter any parameter value such as attachment rate.
Covalent bond formation between proteins initiated by the action of oxidoreductases involves at least two sequential chemical steps (Fig. 4).
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