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The vascular activity of tPA is primarily controlled by PAI-1 and the balance between the two regulates fibrinolysis in vessels.
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The function k3(s) thus indicates that the three objects involved (two regulated genes, one regulator) are preferentially close together.
The projections onto transcription factors are constructed by linking every two nodes regulating a common gene; similarly, the projections onto regulated genes are built by linking every two regulated genes sharing a common regulator.
Similarly, projections onto RG nodes can be made by linking every two regulated genes sharing at least one common regulator.
GR regulates a large variety of gene expression in responses to glucocorticoid hormones [3], [4].
We show that phosphorylation of this critical threonine regulates critical structural changes that lead to activation of the protein kinases.
These two regulators probably regulate each other.
The four regulate air traffic into Berlin, which sometimes leads to tension.
Individual investors might have difficulty knowing how to compare the accounts of a company regulated in New York with one regulated in Nevada.
"All 50 states regulate hairdressers," notes NCLC's Chi Chi Wu, an author of the report, "but only four regulate tax preparers.
Fifteen regulated genes belong to the function class amino acid metabolism (AA).
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