Sentence examples for two mediated from inspiring English sources

The estimates of the two mediated effects were equal to a1xb1 = 0.224 for mediation through NLR and a2b2 = 0.166 for the mediation through HADS.

Using this strategy, 12 HIV-envelope-specific monoclonal antibodies (mAbs) were isolated and three mediated potent ADCC activity when compared to well-characterized ADCC mAbs.

This effect was glucocorticoid receptor (GR) mediated and was abolished by GR antagonist RU486.

To this end we have tested different antioxidants for effects on mycolactone mediated reduction of keratinocyte cell numbers.

This study demonstrates that mycolactone mediated cytotoxicity can be inhibited by deferoxamine, suggesting a role of iron and ROS in mycolactone induced cytotoxicity of keratinocytes.

In vitro studies further demonstrated that anti-INA Ab mediated neuronal damage via inhibiting axonal elongation and eventually driving the cells to apoptosis.

Recently, a chimeric mouse model for human immunity against P. falciparum was used to show that the Ab Fc region plays an important role in Ab mediated protection against erythrocytic stage malaria parasite infection [34].

To examine directly whether the effects of Dex on body fluid control were GR mediated, we used RU486 to determine if the effects of Dex on body fluid control were depended on activation of the GR.

This supports the hypothesis that Fkbp5 is critically involved in regulating GR sensitivity and higher baseline levels of Fkbp5 mRNA result in a higher resistance of the GR to glucocorticoid hormones, as GR mediated induction of Fkbp5 mRNA was proposed as a readout of GR sensitivity [39], [40].

The observations that METH causes oxidative stress [95] and that METH-induced toxicity can be prevented by blocking the DA D1 receptor with SCH23390 [9] suggest that METH might induce Hmox1 transcription via two mechanisms, one mediated by generation of oxygen-based radicals and another occurring via receptor stimulation since DA can cause cell death by stimulation of DA D1 receptor [59], [96].

The second strategy has a strong direct positive effect on place reputation as well as two positive mediated effects though place brand adoption and reducing conflicts among stakeholders.