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There are two marketed vaccines, and Chinese and Indonesian scientists have developed others.
The relative bioavailability of ibuprofen gel compared to the two marketed products was 228.8% and 181.0%.
Compounds 1 5 were even more active than metronidazole and nitazoxanide, two marketed first-line drugs against giardiasis.
The pharmacokinetic properties of the optimized formulation were compared with those of two marketed products in rats.
There are now two marketed fully human therapeutic MAbs, adalimumab and panitumumab, and several dozen more in various stages of human clinical testing.
Notable among these are the HIV-protease inhibitors Agenerase® and Lexiva®, Vertex's first two marketed drugs, as well as the anti-inflammatory compounds Pralnacasan® and VX-765, both oral blockers of the IL-1 beta converting enzyme.
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