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Migraine is divided into two major subtypes: migraine without aura (MwoA) and migraine with aura (MwA) [2].
The clinical separation of the two major subtypes (ADC vs SqCC) has significant impact on the targeted therapy.
The two major subtypes of non-small cell lung cancer, lung adenocarcinoma (ADC) and squamous cell carcinoma (SCC), account for almost 80% of all subtypes of NSCLC.
The CagA protein is one of the virulence factors of Helicobacter pylori, and two major subtypes of CagA have been observed, the Western and East Asian type.
Central to this work was the identification of two major subtypes of KRAS-mutant cancers with distinct effector landscapes and tractable therapeutic vulnerabilities.
There are two major subtypes of T cells: the killer T cell and the helper T cell.
In humans, COPD includes two major subtypes, chronic bronchitis and emphysema.
Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria.
Two major subtypes exist in the brain, those comprised of α4β2 and those comprised of α7 subunits [1], [2].
Here, we found pre-treatment genetic variation was robustly associated with outcome of treatment in the two major subtypes of genotype 1.
Two major subtypes of DLBCL are identified by their genetic activity [5], [6]: activated B-cell-like (ABC) subtype and germinal center B-cell-like (GCB) subtype.
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