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Hamdi owns two machinery workshops, one in the town of Minyat Sammanoud, another in Kuwait, where he lives full time.
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Here, the complete reconstitution of endosome fusion using Rab5 and SNARE proteins highlights the functional relationship between these two machineries.
For instance, in the case of the EGF receptor (EGFR) that is under intensive investigation, two machineries for internalization have been proposed [3].
During reversals, the two machineries switch polarity synchronously.
DNA replication involves two machineries, DnaE and PolC.
Thus, osteoclasts use at least two machineries for cell-cell interaction during in vitro secondary fusion.
The initiation of replication usually represses transcription (1) to prevent the collision of the two machineries (2).
Would it be possible that the two machineries – for DNA replication and for protein turnover – communicate with each other, with each of them relying on the other?
Caspase-3 can be activated through two machineries, namely the mitochondria-related apoptosis protease-activating factor-1/caspase-9/caspase-3 cascade, and Fas-associated adapter protein/caspase-8/caspase-3 cascade which is the extrinsic apoptotic pathway [ 57].
Production rates can be many times greater than that of Axminster looms; one machinery manufacturer has developed a yarn looping technique whereby the backing is pierced by a needle and the pile is then blown through the resulting opening.
Since neurotransmitter release relies on complex interactions between multiple cellular components, we speculate that the cross-talk between CSPα chaperone machinery and the stress-induced Hsp40 is important in maintaining functionally competent synapses.
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