Sentence examples for two immunizations of modified from inspiring English sources

We show that two immunizations of modified non-replicating mRNA encoding influenza H10 hemagglutinin (HA) and encapsulated in lipid nanoparticles (LNP) induce protective HA inhibition titers and H10-specific CD4+ T cell responses after intramuscular or intradermal delivery in rhesus macaques.

After two immunizations, 83.3% of the patients reached seroprotective titres.

In two different experiments, two immunizations with 300 μg of pNJEME by intramuscular (i.m).

This finding raises the question of whether an effective immunization regimen can be limited to two immunizations, or alternatively, how the time interval between second and third immunization could be optimized.

One immunization was sufficient for the accelerated clearance of the infection from mouse lungs, whereas complete protection was achieved after two immunizations.

Two booster immunizations of 400 μg were given 1 month and 4 months after the primary immunization.

Two immunization and challenge experiments were performed.

Mice received a total of three immunizations at two week intervals.

Importantly, Ad5 immunizations failed to boost following the first immunization, whereas DNA responses were continually boosted with all four immunizations demonstrating a major advantage of these improved DNA vaccines.

Differences in the immunization schedules and combination of vectors applied may account for the discrepancies between both works, indeed other studies demonstrated that epitope immunodominance hierarchies observed upon DNA-DNA immunizations can be modified after heterologous prime-boost regimens [38].

One difference between the studies is the number of DNA immunizations: four DNA immunizations with improvement seen after three immunizations, compared to two followed by MVA vaccines.