Q73 mHttex1-split-GFP exhibited a four fold decreased mobility relative to intact Q73-GFP (mean D± standard errors of 22.8±0.7 vs. 6.5±0.5) (Fig. 4E).
AIP1 expression levels were around three fold decreased in GABI_465B06 homozygote plants (here denoted as AIP1KD) (Fig. 9b).
Exclusive breastfeeding for up to six months was associated with a three to four fold decreased risk of transmission of HIV compared to mixed feeding breastfeeding in several African studies.
In comparison to mock-transfected cells, electroporation with RUNX1-CBFA2T1 siresultedulted in a ten- to twenty fold decreased clonogenicity in both single cell expansion (data not shown) and colony formation assays (fig. 2).
Quantitation with primers that distinguish between the two isoforms demonstrated a two fold increase in the ey isoform concomitant with a two fold decrease the ey(2a) isoform (Fig. 3B, right panel).
A two fold decrease in the Kd value for the non-ferrated siderophores as compared to ferrated siderophores in addition to the spatial segregation of the two species, indicates that rSBD shows a relatively higher affinity for non-ferrated siderophores.
Tumor growth was strongly reduced within lungs of Bmi1−/−BXB11 mice (Figure 2B) in two ways, first there was an approximately two fold decrease of tumor numbers between two weeks and three months of age (Figure 2C) and second the volume of surviving tumors decreased (Figure 2D).
Our ChIP results demonstrated that the deleterious effect observed on HIV-1 replication with mutant viruses occurs (at least partly) at the transcriptional level since we measured a ∼ two fold decrease of the PMA-mediated RNAPII in vivo recruitment to the viral promoter when the three intragenic AP-1 sites were mutated simultaneously.
QRT-PCR analysis revealed a two fold decrease of target transcript levels in affected animals.
Surprisingly, this study found a two fold decrease in cholesterol/unit-wet weight of aorta.
The result is a two fold decrease in the efflux R12 and PC concentration (see Figure 5).
