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"two fold decrease" is a correct and usable phrase in written English.
You can use it to describe a decrease in something by half. For example, "The number of people coming to the event saw a two fold decrease compared to the previous event."
Exact(8)
A two fold decrease in the Kd value for the non-ferrated siderophores as compared to ferrated siderophores in addition to the spatial segregation of the two species, indicates that rSBD shows a relatively higher affinity for non-ferrated siderophores.
Quantitation with primers that distinguish between the two isoforms demonstrated a two fold increase in the ey isoform concomitant with a two fold decrease the ey(2a) isoform (Fig. 3B, right panel).
QRT-PCR analysis revealed a two fold decrease of target transcript levels in affected animals.
Surprisingly, this study found a two fold decrease in cholesterol/unit-wet weight of aorta.
In contrast, inhibition of MP1 expression resulted in a greater than two fold decrease in Akt phosphorylation.
The result is a two fold decrease in the efflux R12 and PC concentration (see Figure 5).
Similar(52)
Both 44 h and 72 h after siRNAs transfection, ADAR1 knockdown cells had ∼two fold decrease in the average editing level of Alu elements (n = 6 Alu elements, p<0.04 according to Wilcoxon signed-rank test) (Figure 4C).
All four mortality estimates were within 10% of their baseline value unless the effect of HAART was below a two-fold decrease in HIV mortality.
The root of this almost two-fold decrease in domestic gas demand then is caused by an increase in volume of LNG imports, mostly from Canada.
However, this decrease was not linear: a four-fold increase in injection rate led to a two-fold decrease in MTT.
More than six-fold increase and two-fold decrease has been observed in the emission intensities of λ2 and λ1 peaks, respectively, when the value of 'x' changes from 0.01 to 0.1 in Zn1-x Mn x S nanocrystals.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com