We present tools based on Mashup that achieve state-of-the-art performance in three diverse functional inference tasks: protein function prediction, gene ontology reconstruction, and genetic interaction prediction.
Thirteen genes, including two regulating cell cycle, one transcription factor, one involved in B-cell differentiation and apoptosis, four of diverse functions and four of unknown function, showed downregulation following ODN CpG-2006 treatment (Supplementary Table 2).
The reduction of N-cadherin, Bves and connexin-43 is of particular interest because these three proteins have diverse functions at the disc in the regulation of force and electrical transduction.
Supercontig 1.429 has 25 annotated genes, 12 of which encode cuticle constituents, eight are hypothetical proteins and the remaining five are associated with diverse functions such as metabolism, transcription, protein kinases, extracellular matrix glycoproteins and low-density lipoprotein receptors.
Therefore, it appears that lineage CNSs and genes are functioning in two diverse arenas to ensure thorough overall accurate functioning of the plant.
The TRP vanilloid (TRPV) subfamily consists of six homologous members with diverse functions.
These identified phosphoproteins were categorized into seven major classes with diverse functions: 80.6% were related to binding affinity (45.3% to binding affinity associated with regulation of gene expression and catalytic activity, and 35.3% to binding affinity related to carbohydrate transport, biosynthesis, and metabolism).
The low expression level of the zebrafish esr2a gene in control and exposed embryos (Figure 1F) indicates that the two ERbeta proteins may have diverse functions during development.
We study this problem for a simple safety protection system consisting of two diverse channels performing the same function.
Sixteen randomly targeted proteins of diverse functions, fused to the eGFP were identified and analyzed in living cells by epifluorescence microscopy, demonstrating the suitability of the novel tool for massive, random production of fluorescent proteins and for following of these proteins with different localizations inside the prokaryotic cell.
