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In contrast, a set of genes were found differentially expressed between seasons and most of them fall into two distinct expression patterns (H-L-L and L-H-H).
This is an underestimate since these genes are expressed at significantly higher levels compared with genes having two distinct expression levels (p < .001, Additional file 7: Figure S5C), which improves the statistical power to detect differential expression of homoeoloci.
Two distinct expression patterns emerged after clustering of the state data for circadian genes from our manually created learning dataset.
After hierarchical clustering, two distinct expression patterns were observed with approximately 40% down and 60% up-regulated in the PPARγ KD.
Studies using Northern blotting and cloning methods have clearly documented two distinct expression patterns of EBV miRNAs in EBV-infected B lymphoma cells and EBV-positive NPC cell lines [6].
Using a novel image processing method which is capable of directly analyzing worm images, we found that bright worms (after normalization to remove variation between bright and dim worms) had expression patterns that correlated with other bright worms but that dim worms fell into two distinct expression patterns.
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Less than 10% of differentially expressed genes had three distinct expression levels (e.g., 'A > B > D') in shoots (27/391 genes) or roots (34/417 genes).
Clustering analysis of these differentially expressed genes pointed out six distinct expression patterns during root development.
Without considering the 7 genes expressed by all MRSA strains, ten distinct expression patterns of virulence markers were found during MRSA infection of RHE in vitro (Table 3).
This module has the intrinsic capacity to generate four distinct expression states, each characterized by the expression of a particular combination of pair-rule genes or expression mode.
Comparison of miRNA expression profiling between embryonic liver and adult liver or embryo without liver revealed four distinct expression patterns (Figure 4), which can facilitate understanding of their possible roles during human development.
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