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Among all the synthesized compounds, only two compounds, namely 4g and 4n were identified to be promising in vitro.
Therefore, two compounds namely M-1 and M-2 were purified from Origanum vulgare L. and were identified as carvacrol and thymol, respectively.
Furthermore, an excellent affinity is also obtained thanks to hydrophobic nature of those two compounds, namely the carbon and the IL mixture.
In the network model we consider, capillaries are supplied with two compounds, namely glucose and oxygen, which can then be transferred to the other compartments.
Two compounds, namely 3-methyl-2-butanone and octanal, were detected during all experiments, and a further two, acetone and 2-heptanone, were detected in all samples but one.
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Consequently, four compounds, namely apigenin, quercetin, gallocatechin and myricetin, were suggested to have high binding potency to Akt active site.
Among the sulfur volatiles, four compounds, namely dimethyl sulfided, dimethyl disulfide, s-methyl thioacetate and 3- methylthio) propionaldehyde, were observed in all the 19 CCA samples.
Meanwhile, four compounds namely; 5c, 6a, 6f and 8c exhibited appreciable antifungal activity with MIC values range 33 40 mg/mL comparable with clotrimazole (MIC 25 mg/mL).
The assay revealed that four compounds namely rac-bicyclo[3.2.0]hept-2-en-6-one, benzyl ethyl sulfide, thioanisole and 3-phenylpentane-2,5-dione triggered significant NADPH consumption, which was evidenced by the phosphate production (Additional file 1: Table S2).
Demerdash et al. have isolated four compounds, namely; 1-dehydrogingerdione (249), ar-turmerone (250), -caryophyllene oxide (251) and α-turmerone (252) from a commercial powdered sample purchased from a local market in Mansoura, Egypt [192].
As a result, seven compounds namely; 5a, 5c, 5d, 6a, 6c, 8b and 8c showed a promising broad spectrum antibacterial activity against both Gram-positive and Gram-negative strains.
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