Sentence examples for two aml from inspiring English sources

Many Mendelian CNVs, that are present throughout the entire genome [8], were seen in the two AML samples (table 3).

Additionally, 50 nM of NSC606985 also effectively reduced C/EBPα protein together with the cleaved activation of PKCδ (Figure 1B) and apoptosis induction (data not shown) in primary leukemic cells from bone marrow (BM) of two AML patients.

This allowed us to identify 49 upregulated and 111 downregulated probes (corresponding to 40 and 88 genes), which represent to a novel candidate gene set associated with development of full leukaemia in these two AML mouse models (Figures S3, S4 and Table S2 in Supporting Information S1).

Our finding that downregulation of Gata2 is a common feature for two AML mouse model systems suggests that abrogation of a Gata2-dependent transcriptional program may contribute to leukaemogenic transformation which is supported further by low GATA2 expression found in large-scale human AML datasets.

Two AML patients (11%) achieved CR or CR without platelet recovery.

Clinical characteristics of the two AML patients are shown in Table 1.

The first analysis directly compared the expression profile between eight AML samples without FLT3/ITDs (FLT3/wild type (WT)) and five AML samples with high FLT3/ITD-AR (FLT3/ITDH-AR).

All seven AML cases were female, with median age at AML diagnosis of 48 years (range 34 to 72), versus 66 years in the female general population.

Forty-two AML patients were enrolled in the study.

All AMLs (except one: AML 2003-114) were dependent on cytokines for growth on stroma.

One AML sample had a FLT3 receptor tyrosine kinase domain mutation (TKD).