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It is unknown whether twin outcomes are more similar than unrelated individuals due to genetic similarity, or more different than unrelated individuals because of increased illness severity of one twin, usually the "B", or second twin.
We excluded duplicate publications, studies published only as abstracts, those involving fewer than 10 patients, and those that examined outcomes in multiples unless stratification was done for singleton versus twin outcomes.
Similar(58)
While the focus of increased twinning has been associated with dichorionic twins relating to assisted conception techniques, data are now indicating that these techniques also lead to increases in monochorionic twins and outcomes in these twins are particularly poor.
Reductions from triplets to twins and now from quadruplets to twins carry outcomes as good as those of unreduced twin gestations.
There are limited data on how maternal age is related to twin pregnancy outcomes.
Further examination of twin clinic outcomes is therefore essential.
Within a single centre, maternal and neonatal twin pregnancy outcomes varied significantly by model of care.
There were 1.9% (n = 44) twin pregnancy outcomes and 0.2% (n = 4) abortions or still births during the observation time.
This brings us to the most counterintuitive finding of this study: namely that a history of eating disorders was associated with twins, an outcome ordinarily associated with high fecundity.
We documented that these twins had very different clinical outcomes with twin A being relatively healthy compared to twin B. Associated with this slower disease progression in twin A, we found phylogenetic differences, higher growth rates, and higher genetic diversity in the HIV population and higher recombination rates in rt.
While the stories described are devastating for the families involved, they are worst-case scenarios that do not represent the majority of twin pregnancies and outcomes.
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