Exact(3)
But the third time round really did confound the odds: although the Guinness Book of Records documents an 18th-century Russian woman who gave birth to 16 sets of twins, the chances of a third twin conception are very unlikely.
The RR of a congenital anomaly in a singleton birth from a twin conception and twin births from a twin conception is 2.40 (95% CI: 1.34 4.29; P < 0.01).
Of the 618 women studied, 547 had a diagnosis of complete mole, 13 complete mole with a twin conception and 58 partial moles.
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It's time to drive a stake through the heart of Descartes's twin conceptions of animals as mindless meat machines and the human mind as totally separate from the body, and then nail the coffin shut for good.
The number of twin conceptions notified to the MPR during the 7 years was 3311.
Among 3311 twin conceptions, both conceptuses were lost at <16 weeks gestation in 67, and one conceptus in 142 conceptions.
This is of a similar order of magnitude as found for twin conceptions that result in twin registered births.
Thus, for twin conceptions where one fetus is spontaneously or therapeutically aborted, the surviving conceptus is counted as a singleton birth.
As is the case for twin conceptions with early loss of one conceptus, the prevalence of congenital anomalies in triplet conceptions with an early loss of one conceptus was significantly different from singleton pregnancies (RR: 5.43; 95% CI: 1.86 15.82; exact P = 0.017).
In addition to an inflation of the prevalence of congenital anomalies in singletons owing to twin conceptions being registered as singletons following very early loss of a co-conceptus, there is another possible source of bias in the estimation of RR.
"The technology that made the twins' conception and birth possible, it is safe to say, was not contemplated by Congress" in 1939 and 1965, when those provisions were enacted, Justice Ruth Bader Ginsburg wrote for the court.
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