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22 29 The use of a once-daily evening dose of 400 µg was based on a clinical trial programme, which demonstrated that 400 µg is near the top of the therapeutic dose-response curve in persistent asthma, 22 that once-daily was as efficacious as twice-daily dosing 29 and that evening may be superior to morning dosing.
Daily oral dosing with STX641 (40 mg kg−1 p.o.; daily) was equally as efficacious as the twice weekly i.p. dosing regime: tumours increased in size by 803% ±101 s.e.e
In other studies, higher doses of FF once-daily have proven to be as efficacious as FP twice-daily.
Also, using the US Food and Drug Administration's equation to estimate the human equivalent doses, the clinical trial dose was three-fold higher than the efficacious preclinical dose in mice [ 10, 11], and twice as high as in the MIDAS trial [ 7], raising questions about whether the dose may have been too high, potentially exacerbating oxidative damage.
Fabrications are as efficacious as facts.
By 2020, "my dream is for Duolingo to be as efficacious as a human tutor.
Like, twice as well.
Twice as merry as grigs.
Twice as many as before.
It's twice as fast!
Lost twice as much as I did.
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