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Thus, GATA2 affects bone turnover via MSC-autonomous and indirect effects.
Mizushima, N. & Klionsky, D. J. Protein turnover via autophagy: implications for metabolism.
In semiarid sites, however, microbial biomass exerted significant direct positive effects on all soil N-hydrolyzing enzymes, suggesting strong microbial regulation of SON turnover via enzymatic mineralization.
Structural equation modeling indicated that the direct effect of microbial biomass on soil amidase was insignificant in arid sites, indicating that microbial SON turnover via enzymes is relatively weak.
Ubiquitination alters protein turnover via proteasome-mediated degradation of proteins (Harrison et al., 2016; Leithe 2016; Yamano et al., 2015; Lechtenberg et al., 2016).
EL5, like ATL9, is an E3 ubiquitin ligase and is hypothesized to play a role in defense responses through protein turnover via the UPS [22].
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When work relationship closeness is high, the indirect effect of psychological ownership on turnover intention via territoriality is not significant (b = –.01, boot SE =.02, 95% bias-corrected CI= [ .06,.02]).
Specifically, when work relationship closeness is low, psychological ownership has an indirect effect on turnover intention via territoriality (b = –.06, boot SE =.02, 95% bias corrected CI= [ .11, –.03]) and a 95% bias corrected confidence interval around the bootstrapped indirect, which does not contain zero.
Mcl1 is further regulated post-translationally, with constitutive turnover occurring via ubiquitin-mediated degradation through the Huwe1 Hect E3-ligase.
We showed previously that deSUMOylated phospho-PR function as hyperactive receptors but also turnover rapidly via the ubiquitin-proteasome pathway.
Also, TSH deficiency could be partly responsible for the skeletal loss seen in thyrotoxicosis [ 23], because it has been proposed that TSH may be a direct negative regulator of bone turnover acting via the TSH receptor on both osteoblasts and osteoclasts [ 24, 28].
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