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Since ciliary proteins are subjected to significant mechanical stress, their function may require a relatively high level of turnover to replace damaged proteins.
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If this group disappears from the U.S. labor force due to mass deportations or the loss of work permits, 700,000 would lose their jobs and employers would have to pay $3.4 billion in turnover costs to replace them, the report says.
Given the role of lipids as key structural components of cellular membranes, and also in signalling and intracellular transport processes, we hypothesise that a differential regulation of lipid metabolism was induced in association with an increased rate of cell proliferation and turnover, and/or to replace lipids damaged by oxidative stress.
Tightly related to the aging process, mitochondrial turnover is essential to replace damaged mitochondria with functional, replicating organelles.
This will lead to greater turnover because administrators will have financial incentives to replace experienced teachers with less experienced teachers.
This usually results in increased matrix turnover involving increased matrix synthesis in an attempt to replace essential structural components.
In contrast, due to the slow turnover of αvβ3, long-term treatment was required to replace existing pools of αvβ3 proteolytically activated by MT1-MMP at the cell surface and to inhibit migration.
These data demonstrate that fst RNAi) animals that fail to produce new tissues at wound sites continue to replace aging cells for tissue turnover, indicating the specificity of requirement for fst under these experimental conditions for regeneration.
And since the federal Transportation Security Administration hired and trained employees to replace the low-wage, high-turnover security staffs used by contractors, some travelers said, the screening process seems easier.
The main role of adult stem cells is to maintain tissue homeostasis, and to replace cells lost due to normal tissue turnover, injury or disease.
Each time a worker quits a fast-food job, where turnover rates are exceptionally high, it costs the employer $4,700 to replace them.
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