It is possible that either the parallel action of P-body and spliceosome-mediated decay in RNA turnover or the need to turnover potentially deleterious improperly spliced transcripts in the cytoplasm explain both the P-body induction and genetic interactions of splicing mutants.
When asked about the number of preseason games that most teams play, Aiello said that in 1994, the coaches "came to strong consensus that four preseason games was more necessary than ever, in terms of developing teams because of the increased roster turnover and the need to develop continuity".
It is particularly useful for complexes that must balance a biological requirement for high turnover with the need for specific binding, such as electron transfer complexes.
Cationic radium is a calcium mimetic (located in the same column of the periodic table as calcium), and as such naturally targets areas of bone turnover without the need for a carrier.
Finally, MCA revealed the sensitivity of the system to the protein turnover rates, highlighting the need for careful measurement of these parameters.
Moreover, if the minimum wage reduces employee turnover, this also reduces the need to hire new personnel, which is also associated with higher training investments, as argued above.
The higher protein turnover rates may underlie the need for increased levels of translational machinery.
In our study, a lack of support for staff was regarded as a factor that contributed to nursing turnover, and participants highlighted the need for quality preceptorship for new graduates.
The high turnover of intracellular metabolites highlights the need for reliable, reproducible quenching techniques for microbial metabolomics.
Most importantly, these results reveal the potential of rate heterogeneity among lineages to severely bias some turnover rate estimation methods and the need of further evaluating the performance of these methods in a more diverse sampling of gene families and phylogenetic contexts.
