On the curves k(γx) the turnover region is very well defined for relatively low frictions in the isotropic case, while for the anisotropic case it is shifted towards much higher γx values.
Regardless of H3.3 equilibrium levels, H3.3 dissociation rates were found to be invariably high compared to low H3.3 turnover at regions flanking binding sites of chromatin remodelers.
Seasonal migration and rapid turnover within regions is sustained by the invasion of 'fertile epidemic grounds' at the end of older epidemics.
Yet, prior to population turnover (2003), regions were not strongly differentiated indicating that gene flow between valleys over time could erode the effects of founding events quite quickly [ 18].
The increased rate of cell turnover in regions with hemodynamic stress has been associated with accelerated telomere attrition and with endothelial cell senescence, which further contributes to endothelial dysfunction and intimal hyperplasia [ 26– 29].
This also indicated that some other factors could not be determined by BMD measurement, such as architecture and bone turnover in different regions of the skeleton.
In early adulthood (PN60), we assessed basal neurotransmitter content and synaptic activity (turnover) in brain regions containing the major 5HT and dopamine projections.
In wheat, fast rates of TE insertion and deletion result in rapid turnover of intergenic regions, which can affect neighbouring genes [ 67].
Lower H3.3 turnover at genic regions may partially be explained by gene body H3.3, which is typically exchanged at a low rate.
Our results reveal a novel function of the Mst2 complex in regulating histone turnover at heterochromatin regions to counteract heterochromatin spreading.
