Sentence examples for turnover of type from inspiring English sources

Turnover of type IX collagen by proteases is an early event in degenerative joint disease.

97– 99 Therefore, inhibition of cathepsin K could affect the turnover of type I collagen in organs other than bone.

However, the normal turnover of type II collagen in the body is relatively low, suggesting that significant changes in systemic levels may be expected to be due to pathological turnover from a single joint [ 33].

IL17 increases the turnover of type I collagen through both inhibiting its synthesis and promoting its breakdown [ 35], and members of the IL17 cytokine family members are inhibitors of human hematopoietic progenitor proliferation [ 36].

Turnover of type IV collagen is known to be very slow unless there are inciting injurious stimuli that activate the specific BM degrading enzymes: matrix metalloproteinase(s) MMP-2 (constitutive) and MMP-9 (inducible) [ 31- 34].

The aim of this work was to develop a novel, competitive ELISA for measuring MMP-9-mediated turnover of type IV collagen and to measure the neoepitope 1438'GTPSVDHGFL'1447 (CO4-MMP) in two complementary experimental models of liver fibrosis induced by bile duct ligation (BDL) or carbon tetrachloride (CCl4).

However, as ICTP fragments are destroyed by cathepsin K [ 31, 54], the MMP turnover profile of type I collagen may be masked under normal physiological bone turnover.

Fluctuations in the turnover rate of type 2 cells are effectively suppressed by high-gain feedback without introducing any oscillatory tendency.

Increased turnover of AEC type II is associated with decreased telomere length which in turn will lead to AEC type II senescence.

With regard to the possible continuous turnover of collagen type II and proteoglycans in the articular cartilage matrix, the current experiments may provide some additional information.

The turnover of wild-type and resistant HBV was 2.6×106 and 1.8×106 virions/day, respectively.