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We also quantified changes in biomass composition and confirmed turnover of macromolecules by applying [U-13C]glucose and [U-13C]xylose tracers.
Interestingly, proteasomes, which also play an important role in the turnover of macromolecules, are themselves degraded by autophagy (Cuervo et al. 1995).
Some general response mechanisms to low temperature include higher turnover of macromolecules, tighter maintenance of intercellular pH, greater osmotic regulation, and motility, cessation of biomass production, and reduction of the activation energy before a pre-exponential growth phase [ 24, 56].
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Plant vacuoles are highly dynamic, multifunctional organelles that are the primary storage and turnover sites of macromolecules.
Autophagy is an essential process for the lysosomal turnover of cellular macromolecules and organelles.
As TIMP-3 can inhibit both MMPs and ADAMTSs, it is a central regulator of normal turnover of cartilage macromolecules.
Interestingly, the proteasome pathway controls via transcriptional and posttranslational mechanisms the concentration and turnover of several ECM macromolecules (including proteoglycans/glycosaminoglycans, MMPs/TIMPs, and collagens) [ 157].
Basal autophagy primarily functions as a housekeeping mechanism, ensuring proper turnover and quality control of macromolecules and organelles.
Long-range nutrient redistribution, from green cells in which the balance of turnover favours net dismantling of macromolecules and cell structures, is thus anatomically feasible in the charophytes.
Autophagy is a self-destructive mechanism that regulates the turnover of intracellular organelles and macromolecules.
Autophagy is a 'self-digestion' sequential process that regulates the turnover of intracellular organelles and macromolecules.
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