Sentence examples for turnover of components from inspiring English sources

5 Importantly, the central position is not necessarily off; the system can have a steady-state level, with turnover of components, as long as energy drives the system.

Reductions in β-oxidation of palmitate have been shown in patient fibroblasts, although it seems that respiratory chain function in these cells is normal, suggesting that the selective turnover of components of the mitochondria (namely, IMM) is defective (Hall et al., 1991; Palmer et al., 1992; Dawson et al., 1996).

This LT-induced phenotype is the consequence of altering major components of the mammalian cytoskeleton and microtubule network, causing a state of permanent paralysis where turnover of structural components is greatly reduced.

Other possible sources of fatty acids could be from increased endogenous synthesis or from turnover of cellular components.

This mechanism may contribute to control the turnover of membrane components for repair or degradation after stress.

Autophagy is a degradative process involving lysosomal turnover of cellular components, though its role in human diseases remains unclear.

Autophagy has been identified as a process for the turnover of intracellular components which can be negatively regulated through the intracellular signaling pathway associated with mTOR [29].

Given the large discrepancy between the lifetimes of NMJs and AChRs, there is need for a regulated turnover of NMJ components, which is thought to be mediated by their exocytic delivery and endocytic elimination [2].

To test the hypothesis that Parkin promotes the ubiquitin-mediated turnover of core components of the mitochondrial morphogenesis machinery, we sought to explore the effects of altered Parkin activity on the steady-state abundance of the mitochondrial fission-promoting factor Drp1 and the mitochondrial fusion-promoting factors Opa1 and dMfn.

A study evaluating the turnover of adhesion components in randomly migrating cells implicated p130Cas in regulating FA disassembly, with the apparent rate constant for FA disassembly ∼19-fold lower in Cas −/− MEFs as compared to cells expressing wild type (WT) p130Cas [25].

59 The maintenance of myelin requires continued turnover of its components throughout life.